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A phase 2 randomized trial of survodutide in MASH and fibrosis. New England Journal of Medicine 391.4 (2024): 311-319

( B ) Analysis of plasma parameters (sodium, chloride, urea, creatinine, total cholesterol, glucose, triglycerides, glycerol levels) in saline controls (Saline, n = 9), saline-treated HI animals (HINT, n = 7), HI treated with Exendin-4 (Ex-4, n = 6) and HI treated with Semaglutide (Sema, n = 7), which showed no significant difference between groups except for a statistically significant increase in creatinine in all HI groups

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Even so, understanding what to expect helps set realistic expectations and ensures a smoother experience

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