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A logical extension of this framework is the consideration of another key regulatory system -the gut microbiota, which also makes a substantial contribution to diabetes pathogenesis and interacts with the islet apparatus within the framework of the gutpancreas axis

doi: 10.1053/j.gastro.2020.12.058

New insights into AMPK, as a potential therapeutic target in metabolic dysfunction-associated steatotic liver disease and hepatic fibrosis

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A germline microdeletion of NF1 and flanking loci affect 510% of NF1 patients [16]