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The medication was designed for continued use, not discontinuation

doi: 10.3390/medicina57050418 7 KomaroffALLipkinWI

Furthermore, some were these drugs were associated with potential undesirable effects, such as the risk of heart failure or fractures (complications that are especially prevalent in patients with CKD), this is the case of thiazolidinediones, and the use of sulfonylureas and insulin are associated with weight gain or the risk of hypoglycemia

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