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Oxidative Stress as a Common Key Event in Developmental Neurotoxicity

115 M1 macrophages mediate excessive inflammatory responses, cytotoxicity and tissue damage by producing proinflammatory cytokines and chemokines, 116 whereas M2 macrophages aid in reducing inflammation, tissue restoration, and cellular proliferation through the secretion of anti-inflammatory cytokines such as IL-10 and IL-4

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