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The researchers argued, The increased risk associated with short-acting analogs needs further studies to validate these findings. The possible protective effect of GLP-1 receptor agonists against AMD may be primarily attributed to their ability to mitigate chronic retinal inflammation and oxidative stress, which are pivotal in the pathogenesis of AMD, the authors explained in their paper

The intravenous method is a much higher dose level of 380mg and is given once a month in a medical clinic

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Overall, 72.5% of participants experienced at least one disruption in their GLP-1 treatment and 11.1% had multiple disruptions, Medeiros reported at ENDO 2025