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For years, Melanie went from doctor to doctor, trying all sorts of therapies and diets

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Given this close relationship, scientists have hoped that semaglutide and similar drugs that mimic the hormone GLP-1 (already approved to treat obesity and diabetes) could be an effective treatment for MASLD/MASH as well

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The SELECT cardiovascular outcomes trial published in 2023 added a cardiovascular benefit signal: semaglutide reduced major adverse cardiovascular events by 20% in overweight and obese patients with established cardiovascular disease, independent of diabetes status