Turner reiterates that as long as youre increasing your dosage incrementally, they dont tend to be too bad: While uncomfortable, they often improve as your body adjusts to the medication, he adds
Suddenly stopping it can lead to adrenal insufficiency, a potentially life-threatening condition where your body cannot produce enough natural steroids
Patients should call 999 or attend the nearest Accident & Emergency department if they develop: Difficulty breathing or swallowing Swelling of the face, lips, tongue, or throat (angioedema) Widespread urticaria (hives) or severe skin rash Dizziness, light-headedness, or loss of consciousness Rapid heartbeat or chest tightness These symptoms may indicate anaphylaxis, a life-threatening allergic reaction that requires urgent treatment with intramuscular adrenaline and supportive care
GLP-1 agonists themselves slow gastric emptying as part of their mechanism, potentially amplifying nausea or fullness during high-progesterone phases
The injectable form also has an indication to treat patients with noncirrhotic metabolic dysfunction-associated steatohepatitis with moderate to advances fibrosis (stage F2 or F3)
