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167,168 In hepatocytes, elevated lipid load and insulin resistance increase mitochondrial -oxidation activity, accompanied by electron leakage and respiratory chain disruption, resulting in substantial ROS production, which exacerbates lipid peroxidation, autophagic dysfunction, and pyroptosis
Indian J
- Descubrimiento a partir de la carne: la L-Carnitina fue descubierta y aislada por primera vez como un componente del tejido muscular animal en 1905 por los cientficos rusos V
Chemotherapy-Induced Polyneuropathy Chemotherapy-induced peripheral polyneuropathy affects up to 80% of patients treated and constitutes a series adverse event, the occurrence of which may require anti-cancer therapy dose adjustment [69]
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