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2026;doi:10.1016/s0140-6736(26)00717-8 Endocrine Society

3.3.2 Effect of metformin on offspring malformations in patients with polycystic ovary syndrome The period of early pregnancy is critical for organogenesis and the potential teratogenic effects of drugs

52 In addition, inositol compounds called inositol phosphates act as second messengers to several hormones, including insulin and FSH, by transmitting external signals to the working interior of cells

Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network

By helping to neutralise free radicals before they can damage DNA and cellular structures, it may support healthier mitochondrial function, the energy powerhouses that keep cells performing as they should.[4] There is also a detoxification dimension that deserves attention