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doi:10.1111/j.1473-2165.2008.00355.x

These typically subside after a few weeks, especially with gradual dose escalation

207-209 In fact, sleep disruption is one of the diagnostic criteria for multiple mood disorders including generalized anxiety disorder, and preclinical studies show disruption of circadian rhythms (day-night wake-sleep cycles) cause anxiety-like responses

Therefore, they are valuable tools for individuals looking to optimize their fitness and well-being

It is about whether patients have a medical reason that an FDA-approved version cannot meet for example, an inactive-ingredient allergy or a documented need for a different formulation