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Metabolic pathway overlap: Both compounds affect metabolic processes related to weight management and insulin function

--- The Human Study: What They Did The study followed patients diagnosed with chronic knee pain including osteoarthritis, patellofemoral syndrome, and post-injury degenerative changes who had not achieved adequate relief from standard interventions including physical therapy, NSAIDs, and corticosteroid injections

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This increase in excitability may result from neuroexcitatory effects caused by disrupted balance between inhibitory (-aminobutyric acid-mediated) and excitatory (cholinergic) signalling, indicating possible neuronal hyperactivation [157]