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Evidence shows that both medications support weight loss and blood sugar control, with some trials favoring tirzepatide, while reviews emphasize the more extensive long-term research on semaglutide

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On the plus side, neither medication typically causes low blood sugar (hypoglycemia) unless combined with other drugs like insulin or sulfonylureas that can lower blood sugar

So when women begin HRT with weight loss in mind, they often experience ripple effects across their overall physical and mental health too