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Inherited defects in -TTP are associated with a characteristic syndrome called "Ataxia with Vitamin E Deficiency" (AVED)

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doi: 10.1007/s00216-020-02403-3 80 AyaO-SKentaHYoshikiSTakuyaTShihoT-SMinamiIet al

This means that GLP-1 stimulates insulin release only when blood glucose levels are elevated, which significantly reduces (though does not eliminate) the risk of hypoglycaemia