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Though most of the idiopathic infertile males participated in the present study have at least one sperm parameter abnormal, the cumulative spermiogram shows values with WHO, 2010 range

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However, this was predominantly driven by one trial, DECLARE TIMI 58, which included healthier cohorts than other cardiovascular outcome trials (CVOT) involving SGLT-2 inhibitors [103], and this benefit of asthma risk reduction was neutralized when DECLARE TIMI 58 was excluded from the analysis [105]

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