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Featured image: Patient underwent abdominopelvic CT for indication of abdominal pain 36 days before semaglutide initiation and for indication of epigastric pain 140 days after semaglutide initiation

This Gs-biased profile may contribute to sustained receptor signaling with less desensitization, though the clinical implications of signaling bias in GLP-1 therapeutics remain an area of active investigation

References Brzoska T, et al

Signaling Satiety Centers in the Brain In addition to making you feel satisfied after eating by slowing digestion, GLP-1 receptor agonists can also send signals to your brain that reduce cravings

It was 4 months since August, and I was hovering right around the same weight I was when I started what I hoped to be a fast journey to a relatively fit body by my 40th birthday in February