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In mammalian cells, this process is highly regulated and responsive to selenium availability, both at the levels of RNA stability and translation (11,13,14)

Ethics declarations Conflict of Interest The authors declare that they have no conflict of interest

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Avoiding Excess IGF-1 Levels While elevated IGF-1 is beneficial for recovery, metabolism, and body composition, chronically supra-physiologic IGF-1 can carry risks, including potential links to accelerated cellular aging and increased cancer risk in certain populations

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