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Despite their advancement in clinical trials, the pharmacodynamic properties of PF 06882961 and OWL-833 have not been reported and the extent to which these compounds overlap the signalling and regulatory profile of endogenous GLP-1 is unknown

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Initial serology showed positive Treponema pallidum particle agglutination (TPPA) with a low titer (1:2) on the toluidine red unheated serum test (TRUST)

& Muller, S