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Activation of AMP-activated protein kinase (AMPK) under energy stress conditions inhibits acetyl-CoA carboxylase (ACC), reducing fatty acid biosynthesis and limiting PUFA-PL incorporation into membranes

doi: 10.1161/jaha.115.002810 25 WoolfendenSFarrarMAEapenVMasiAWakefieldCEBadawiNet al

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Additionally, in patients diagnosed with the CCC, the HLA types HLA-C*07:04 or HLA-DQB1*03:03 were shown to be significantly linked to ME/CFS status when using the CCC (89)