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GLP-1RA therapy on major adverse cardiovascular events Representative large-scale cardiovascular and kidney outcome trials of GLP-1RAs and their results are shown in Table 1
Libraries were pooled and sequenced on a NovaSeq X sequencing system (Illumina)
These issues dont just compromise the integrity of a trial, they can call into question the entire development program
A randomized trial in 2022 revealed that Wegovy-treated patients experienced a significant 15.8% reduction in body weight compared to Saxendas 6.4% in a 68-week study
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