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47 Taken together, these data suggest the reduced GSH/GSSG antioxidant capacity is insufficient to counter excessive OH production, and that unopposed OH can reach the nucleus to create the oxidative DNA adduct, 8-oxo-dG

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It generates ubiquinol by reducing coenzyme Q10 (CoQ 10 ) via NAD(P)H, scavenges lipid peroxyl radicals, and inhibits phospholipid peroxidation (24)

Mitochondrially-targeted catalase (MitoCatalase) was cloned into the pLenti-CMV-Blast vector (Addgene, 17445) and introduced into H1299 cells as previously described 40

Tirzepatide can help people with type 2 diabetes, obesity, or excessive body fat lose weight and manage their blood sugar levels