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El GLP-1 es degradado de forma rpida en la circulacin por parte de la DPP-4, la cual escinde residuos de alanina o prolina ubicados en la penltima posicin del extremo N-terminal, lo que explica su vida media corta (1-2 minutos) 15 , pero que permite que a niveles fisiolgicos se cumpla su efecto incretina en la CBP 18

The active ingredient in Ozempic is also the same active ingredient in Wegovy

Studies have shown that metformin may actually help lower thyroid antibodies, reduce inflammation in the thyroid tissue, and improve overall thyroid function

Yet, GLP1s are not currently approved to prevent or treat cognitive decline

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