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Some drugs (including colchicine and metformin), as well as vitamins like vitamin C and folic acid, can reduce the levels of vitamin B12 in your body or affect the absorption of it

All About Vitamin B12 Vitamin B12 is an essential vitamin to stay healthy and fit in the long run

Exercise therapy in patients with constipation: a systematic review and meta-analysis

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LEADER [29] and SUSTAIN-6 [30] reported a prespecified renal composite of new onset or persistent macroalbuminuria, persistent doubling of serum creatinine and eGFR 45 mL/min/1.73 m 2 , need for renal replacement therapy (RRT), and renal death