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Duarte S, Rosalen PL, Hayacibara MF, Cury JA, Bowen WH, Marquis RE, Rehder VL, Sartoratto A, Ikegaki M, Koo H
Aliyev et al., 2021)
Most side effects are mild, localized, and transient
Tirzepatide population pharmacokinetics and exposure Schneck 19-study pooled popPK (CL/F 0.061 L/h, half-life 5.4 d, accumulation 1.7x, body-weight covariate +22% at 70 kg / -33% at 120 kg)
Peptide Sequence (IUPAC Condensed): Ac-Ser-Tyr-Ser -Nle-Glu -His-D-Phe-Arg-Trp-Gly-Lys- Pro-Val-NH2 Molecular Formula: C78H111N21O19 Molecular Weight: 1646.8 g/mol Synonyms: Melanotan 1, MT-1 Melanotan I works by mimicking alpha-melanocyte-stimulating hormone (-MSH)
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