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Aggressive media campaigns about its exaggerated effects as a skin lightening agent and over-the-counter availability of this drug have resulted in consumption of improper doses and schedules

doi: 10.1016/j.yfrne.2014.02.001 62 ZhangXvan den PolAN

Cosmetic-grade formulations may contain stabilizers, preservatives, or carrier molecules that alter absorption kinetics or introduce immune response risk when injected

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Ultimately, large randomized trials are needed to distinguish weight-mediated effects from direct anti-inflammatory or neuromodulatory actions