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PAM activity was measured using a previously described radiotracer method (Additional file 1: Supplementary methods) in 24 heterozygous carriers of p.S539W, 27 heterozygous carriers of p.D563G and 21 homozygous carriers of p.D563G and age, sex and BMI matched non-carriers [24, 25]

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Reporting Approach To enhance methodological transparency, elements of systematic review reporting were incorporated to describe the literature identification and selection process

352.204.0094 [gtranslate] Retatrutide and semaglutide belong to the same family of GLP-1based drugs, but they are not built the same