tirzepatide versus semaglutide once weekly beat in the first head to head trial., 72 weeks: 20.2% of body weight lost vs 13.7%. Waist down about 18 cm vs 13 cm (DOI: 10.1056/NEJMoa2416394)., Why: semaglutide hits one SURPASS 2: Tirzepatide Versus Once-Weekly

Spacing oatmeal at least two hours apart from other structured meals prevents your stomach from becoming overloaded during the slower digestion window characteristic of GLP-1 therapy

GLP-1 receptor activation: Slows gastric emptying, reduces appetite, and lowers post-meal blood glucose levels

Rapid Action Adderall works quickly, often within 30 minutes to an hour after taking it

The target gene primer sequence was as follows

Future studies investigating the effects of PAM LoF on food intake and body weight will be required to elucidate the extent to which effects of elevated circulating GLP-1 levels extend beyond glycemic control and to provide greater mechanistic insight