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MECHANISMS OF ACTION OF GLP-1 RAs AND MULTI-AGONIST THERAPIES Incretin-based therapies leverage the physiological roles of gut-derived peptide hormones, principally glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptor (GCG) to address the multifaceted pathophysiology of MASLD

The right dose is the one that produces the desired clinical outcome with acceptable side effects

According to KFF health data, one in eight Americans have already tried a type of GLP-1 drug, and that number is expected to grow exponentially over the next decade

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