IU and dosing math for researchers U100 insulin syringes calibrate volume in international units where 100 IU equals 1 mL, so 1 IU equals 0.01 mL
Doses start very low (0.25 mg weekly for semaglutide) and titrate up slowly
A few commenters recommended that CMS ensure the repository is a neutral clearinghouse and, if CMS engages with a third-party to operate the repository, that the party is free of conflicts of interest
Symptom Monitoring: Even though serious adverse events did not occur in trials, individual monitoring for headache, gastrointestinal symptoms, or unusual effects allows for early detection of tolerability issues and appropriate management adjustments
The longevity medicine community has begun integrating BPC-157 into broader protocols that address the biological underpinnings of aging: chronic low-grade inflammation, impaired tissue repair capacity, gut barrier dysfunction, and declining growth factor signaling