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Vilsbll T, Agers H, Lauritsen T, Deacon CF, Aaboe K, Madsbad S, et al

Activation of GLP-1R leads to an increase in intracellular cAMP and/or calcium, triggering signaling pathways including protein kinase A (PKA), exchange proteins directly activated by cAMP (Epac-2), phospholipase C (PLC), and extracellular signal-regulated kinase 1 and 2 (ERK1/2), thereby mediating effects on glycemic regulation, immune process, and inflammation

However, it also depends on the overall health checkup done by the doctor.

A medical screening is required

Ninety-four genes were identified whose expression was dependent on LAG-1 (activated genes), where ~70% (64) of these were also GLP-1 dependent genes ( S8C Fig