Extended outages If you are facing a multi-day outage during extreme heat, prioritize getting the medication to a refrigerated location
Early detection of weight regain allows early intervention
Average body weight reduction: 5 mg weekly: 16.0% reduction (approximately 35 pounds for a 220-pound person) 10 mg weekly: 21.4% reduction (approximately 47 pounds) 15 mg weekly: 22.5% reduction (approximately 50 pounds) Placebo: 2.4% reduction Percentage of participants achieving clinically significant weight loss: 5% or more weight loss: 85% at 5 mg, 89% at 10 mg, 91% at 15 mg 10% or more weight loss: 69% at 5 mg, 78% at 10 mg, 84% at 15 mg 20% or more weight loss: 32% at 5 mg, 49% at 10 mg, 57% at 15 mg Look at those numbers carefully
In a separate 12-month prospective study of 65 patients with type 2 diabetes mellitus (T2DM) initiating GLP-1 RA therapy (dulaglutide or semaglutide), significant reductions in body weight and BMI were also observed
The mechanism of action involves mimicking two naturally occurring incretin hormones that regulate glucose metabolism and appetite