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found that circ_0001273, as a cancer-promoting factor that upregulates SLC1A5 expression by binding to miR-622, which increases Gln uptake by tumor cells, consequently enhancing tumor growth and inhibiting cell apoptosis (57)

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This helps reduce hunger and improve blood sugar control, which can lead to weight loss

This approach enabled the use of Lani at doses 6,898-fold lower than the dose (30 mg kg 1 ) required preclinically to improve liver metabolism 31