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doi: 10.1016/j.trecan.2018.01.007 Summary Keywords intrahepatic cholangiocarcinoma, rectal metastasis, cancer treatment, tumor marker, pathological features Citation Jiang S, Huang L and Jiang Q (2025) A case report of a rare intrahepatic cholangiocarcinoma with rectal metastasis

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This type of database analysis allows us to get a glimpse at those longer-term outcomes. The study also included a range of GLP-1based medications, from earlier agents such as liraglutide to newer therapies including semaglutide and tirzepatide

Liver injury caused by acetaminophen is initiated by cytochrome P450 (CYP)-mediated bioactivation to N -acety- para -benzoquinoneimine (NAPQI), which is a chemically reactive intermediate that is formed at high levels following overdosage and triggers a complex cascade of events, which ultimately result in hepatocellular necrosis (Hinson et al