On one hand, oxidative stress is recognized to contribute to NAFLD progression, and glutathione is known to protect against NAFLD progression (Liu, Baker, Baker, & Zhu, 2015), although most of those studies have examined glutathione synthesis rather than glutathione redox
found that Bardoxolonemethyl can inhibit chondrocyte apoptosis and ECM degradation induced by oxidative stress in vitro , and reduce OA in vivo (Pang et al., 2021)
A 2023 clinical trial showed that 100 mg/day of supplemental riboflavin in healthy adults increased butyrate production in the colon
Gene Expr
The leading search terms were: oxidative stress, reactive oxygen species, thyroid disease, nutritional antioxidants, thyroid-gut axis, gut microbiome, and antioxidant probiotics