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Because it can take time for metabolic changes to begin, there is a 3-month minimum commitment

These findings indicate that GLP-1RAs have anti-adhesive and anti-thrombotic properties in the endothelium that may delay the development of atherosclerosis [110]

Tirzepatide's efficacy and safety profile is well-established through the SURPASS clinical trial program, which demonstrated significant HbA1c reductions (up to 2.5% from baseline) and weight loss in patients with type 2 diabetes

Journal of Biomaterials Science, Polymer Edition, 19(8), 969-988

This makes it easier to stick to a reduced-calorie diet without feeling deprived or constantly hungry