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Nonetheless, semaglutide facilitated maintaining a stable weight of 117 kg (BMI 54.5 kg/m 2 , WC 128 cm, WHR 0.96), without further weight regain and her HbA1c remained stable at 5.8%

Allergic reactions (extremely rare): Recognize symptoms (rash, difficulty breathing, swelling) Discontinue the peptides immediately Seek emergency medical care if severe Document and report Exclude from further research Unexpected serious adverse events: Clear protocols for recognition and management Access to medical care Documentation and reporting requirements Communication with research oversight bodies Review of protocols if serious events occur Safety Documentation Proper documentation of safety is essential

But theyre not yet proven to work, and there have been no large-scale clinical trials on humansnot even safety data

Why reinvent the wheel when all of our current options work

As older adults with type 1 diabetes are especially vulnerable to hypoglycaemia, target glucose values should be adjusted to minimise the occurrence of hypoglycaemic events