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In the intestine, dietary Fe3+ is reduced to Fe2+ and subsequently absorbed by intestinal epithelial cells [48]

This occurs because the skin's pigment-producing cells, called melanocytes, are destroyed, resulting in the loss of skin colour in affected areas

In the long term, by stimulating GHRH neurons, GHS sustains its receptors by direct effect and also due to association with dopamine receptors to form GHSR1a:DRD2 heteromers 18

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Introduction Heavy metal pollution is an environmental threat that affects ecological systems and living organisms, including plants, animals, and humans