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The identified metabolomic profile had an area under the receiver operating characteristic curve of 0.953

[DOI] [PMC free article] [PubMed] [Google Scholar] 66.Pelletier J.S., Capriotti K., Stewart K.S., Capriotti J.A

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Thus, a functional overexpression of MnSOD, caused by presence of the Ala variant, combined with a potential deficiency of GPx-1, caused by the Leu variant, could potentially create a redox imbalance leading to enhanced hydrogen peroxide flux