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Melatonin enhances salt stress tolerance in rubber tree ( Hevea brasiliensis ) seedlings

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IGF-1type molecules, including IGF-1 LR3, are typically characterized in research as supporting hyperplastic responses rather than direct cell enlargement

doi: 10.1016/0165-1161(75)90046-1 210 ColmanNHerbertVGardnerAGelerntM

Collectively, the synergistic action of AGE-RAGE signaling, metabolic rewiring, and oxidative stress in the DW microenvironment creates a powerful, self-reinforcing circuit that locks macrophages into a persistent M1 state, thereby perpetuating chronic inflammation and impeding the resolution of healing (Figure 3)