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Norleucine-YIHPF (Nle'-Ang-iV), D-Nle-YI, Acetyl-NleYIH, Gamma Amino Butyric Acid- YIH, NleYI-amide, N-hexanoic-YI-(6) aminohexanoic amide (dihexa) were synthesized by Fmoc based solid phase methods in the Harding laboratory

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Of these, 60 sequences were shortlisted based on stability, efficacy, and diversity criteria for further experimental validation

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