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1 Introduction Cynanchum plants have been used to treat a variety of diseases in folk medicine, such as cancer, inflammation, and viral infections ( 21 sterol glycosides, a class of secondary metabolites in Cynanchum plants, are responsible for regulating cellular activities associated with cancer, including cell proliferation, apoptosis, and metastasis ( 21 steroidal glycosides (e.g., dioscin) can have potent anticancer activity by triggering mitochondrial apoptosis, caudatin is structurally unique given its incorporation of an isovalerate side chain and the C-3 glycosylation affords a broader target specificity against Wnt/-catenin and autophagy-lysosomal pathways

One such compound that has gained considerable attention in recent years is glutathione

It has earlier been demonstrated that GSTP1 Val increases catalytic efficiency by several fold towards tobacco-related pollutants benzo(a)pyrene, and diol epoxide as compared to GSTP1 wild type enzyme 39

Bottom line: DSIP remains strictly a research compound

European Journal of Neuroscience, 21 , 21992208