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Theoretically, deficiencies in GPx3 and cystine reduce the ability of the body to counter oxidative stress by virtue of the glutathione pathway and associated enzymes, which may lead to increased ROS in the circulation

VIP also regulates the activity of immune cells, such as T cells and macrophages, promoting a more controlled immune response

ROS generation was detected using a Leica fluorescence microscope (Leica DM6000B) and Leica LAS X software, and the quantitative analysis was performed with ImageJ

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However, in more recent years, the organization has split into two parts (there was a third part, the Life Extension Pharmacy, but it was short-lived and no longer exists): The non-profit organization Biomedical Research and Longevity Society, Inc