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The complex pathophysiology of ME/CFS As a consequence of infection and other stressors, such as poly-trauma for example (181), a state of acute inflammation and aberrant immune activation may occur
10.1523/JNEUROSCI.3885-07.2007 20 ChoiI
Identification of apilimod as a first-in-class PIKfyve kinase inhibitor for treatment of B-cell non-Hodgkin lymphoma
Yet, treatment of disease with antioxidant approaches has nearly uniformly failed (19, 20), perhaps partly because oxidative stress is often compartmentalized or driven by multiple nonspecific (chemical) and specific (enzymatic) pathways
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