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Interestingly, a SLC25A39 -associated human phenome analysis using 4,000 traits in the UK Biobank (n=361,194 subjects) revealed reticulocyte count and hemoglobin concentration as the top significant phenotypes associated with genetically regulated SLC25A39 expression (Extended Data Fig

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2000 Jun;10(2):199-207

At the highest doses, Mounjaro users experienced an average weight loss of about 22.5% of their initial body weight, while Wegovy users saw an average loss of about 15%