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By taking advantage of the increased 14 C atmospheric levels during the Cold War and 14 C incorporation into lipid, the group of Peter Arner and Kristy Spalding were able to calculate lipid age and turnover, demonstrating that lipolysis is defective during aging (235)

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The expression and activity of MLCK1 can be increased by a number of cytokines including TNF- [35,36,37] and IL-1 [38], providing evidence for the role of the immune system signalling in affecting paracellular permeability

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