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In doing so, the Wegovy pill helps you lose weight by: The Wegovy pill can start to reduce your appetite within the first few days to weeks of starting treatment, but it can take several months for you to see significant weight loss results

[DOI] [PMC free article] [PubMed] [Google Scholar] 32.Reed J, Kanamarlapudi V, Choi S

The glucagon receptor agonism is thought to play an important role in hepatic fat reduction: preclinical and early clinical data suggest that glucagon stimulates hepatic fatty acid oxidation and promotes lipid export from the liver, potentially reducing intrahepatic triglyceride content

Hepatology 2006;43:173-181

Incretin effects of increasing glucose loads in man calculated from venous insulin and C-peptide responses