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secondary IR cross-reactivity Key downstream pathways / PI3K-Akt-mTOR and RAS-MAPK-ERK IGF-1 DES comparison / DES is 6-aa truncated, 10x higher potency but even shorter half-life (~20-30 min) Regulatory status / Not FDA-approved for any indication

doi: 10.1245/s10434-014-4215-3 135 LazarevSGuptaVHuKHarrisonLBBakstR

The caffeine may ward off sleepiness, but it wont change how alcohol decreases your coordination, slows your reaction time and negatively affects your decision-making

Review Team: