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10.2174/0929867325666191011115407 16 ChenX.WangX.YangL.XuH.WuY.WuJ.et al (2021)

Over time, meaningful improvements in body composition more lean muscle, less body fat without disrupting how your hormones naturally function

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However, the same hormonal action that makes tirzepatide most effective for weight loss often causes significant early side effects, such as nausea and vomiting, during the start of the treatment or during the escalation phase