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Gut microbiota metabolites and risk of major adverse cardiovascular disease events and death: a systematic review and meta-analysis of prospective studies

Summary: DPP-4 inhibitors lower HbA1c by approximately 0.51.0% (5.511 mmol/mol) in adults with type 2 diabetes by prolonging the activity of incretin hormones to stimulate insulin secretion and reduce glucagon release

These are generally mild and transient

no published trial has evaluated Mod GRF 1-29 as a standalone compound, so every human data point attached to it is borrowed from CJC-1295 studies of the same peptide core

Cumulative damage to keratinocytes DNA leads to skin cancer