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2003 Dec;90(6):1081-5
The B12 used in fortified foods and supplements it is not bound this way and so is easier to absorb
Alpha-lipoic acid may interact with certain medications, and patients should inform their healthcare provider of all drugs and supplements they are taking to avoid adverse interactions
Many drugs look promising in cells, mice, or tissue samples but fail in later stages because: The treatment doesnt work well enough in humans It causes side effects at real doses The effect fades over time The human joint environment is much more complex than the lab So while we are hopeful, there is a long road ahead before this approach could become a real treatment
, Lehre K
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