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Oridonin, a diterpenoid compound isolated from Rabdosia rubescens , was shown to alleviate PI-IBS symptoms in rats by significantly inhibiting phosphorylation of NF-B p65 and downregulating downstream inflammatory mediators such as inducible nitric oxide synthase (iNOS), COX-2, IL-1, and IL-6
There isn't independent clinical data provided here confirming added benefit from these additions in this formulation, so treat it as a bonus rather than a proven feature
McCormick LM, Heck PM, Ring LS, Kydd AC, Clarke SJ, Hoole SP, et al
Is the TriVantage Alexandrite laser safe for dark skin
We conducted a time-course analysis to determine the number of TH + cells in the SNcVTA regions of the mutant and control subjects
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